ORAI1 Antikörper (AA 1-87) (Biotin)

Produktnummer ABIN7146307

Dieses Anti-ORAI1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ORAI1 in ELISA. Geeignet für Human.

Kurzübersicht für ORAI1 Antikörper (AA 1-87) (Biotin) (ABIN7146307)

Target: ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ORAI1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-ORAI1 Antikörper (Biotin)

Bindungsspezifität: AA 1-87

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Calcium release-activated calcium channel protein 1 protein (1-87AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ORAI1

Target: ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))

Andere Bezeichnung: ORAI1

Hintergrund:

Background: Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1 (PubMed:16582901, PubMed:16645049, PubMed:16733527, PubMed:16766533, PubMed:16807233, PubMed:19249086, PubMed:23307288, PubMed:24351972, PubMed:24591628). CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT (PubMed:16582901).

Aliases: Calcium release activated calcium channel protein 1 antibody, Calcium release activated calcium modulator 1 antibody, Calcium release-activated calcium channel protein 1 antibody, CRACM 1 antibody, CRACM1 antibody, CRCM1 antibody, CRCM1_HUMAN antibody, FLJ14466 antibody, Orai 1 antibody, ORAI calcium release activated calcium modulator 1 antibody, orai1 antibody, ORAT1 antibody, Protein orai 1 antibody, Protein orai-1 antibody, TMEM 142A antibody, TMEM142A antibody, Transmembrane protein 142A antibody

UniProt: Q96D31

Pathways: T-Zell Rezeptor Signalweg, BCR Signaling