ORAI1 Antikörper (AA 1-87)

Produktnummer ABIN7146306

Produktdetails anti-ORAI1 Antikörper

Target: ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))

Bindungsspezifität: AA 1-87

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ORAI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Calcium release-activated calcium channel protein 1 protein (1-87AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ORAI1

Target: ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))

Andere Bezeichnung: ORAI1 (ORAI1 Produkte)

Synonyme: CRACM1 antikoerper, ORAT1 antikoerper, TMEM142A antikoerper, RGD1311873 antikoerper, D730049H07Rik antikoerper, Tmem142a antikoerper, orai-1 antikoerper, im:7146264 antikoerper, orai1 antikoerper, tmem142a antikoerper, zgc:109721 antikoerper, orai2 antikoerper, ORAI1 antikoerper, LOC100218031 antikoerper, ORAI calcium release-activated calcium modulator 1 antikoerper, ORAI calcium release-activated calcium modulator 1b antikoerper, ORAI calcium release-activated calcium modulator 1 S homeolog antikoerper, ORAI1 antikoerper, Orai1 antikoerper, orai1b antikoerper, orai1.S antikoerper, orai1 antikoerper

Hintergrund:

Background: Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1 (PubMed:16582901, PubMed:16645049, PubMed:16733527, PubMed:16766533, PubMed:16807233, PubMed:19249086, PubMed:23307288, PubMed:24351972, PubMed:24591628). CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT (PubMed:16582901).

Aliases: Calcium release activated calcium channel protein 1 antibody, Calcium release activated calcium modulator 1 antibody, Calcium release-activated calcium channel protein 1 antibody, CRACM 1 antibody, CRACM1 antibody, CRCM1 antibody, CRCM1_HUMAN antibody, FLJ14466 antibody, Orai 1 antibody, ORAI calcium release activated calcium modulator 1 antibody, orai1 antibody, ORAT1 antibody, Protein orai 1 antibody, Protein orai-1 antibody, TMEM 142A antibody, TMEM142A antibody, Transmembrane protein 142A antibody

UniProt: Q96D31

Pathways: T-Zell Rezeptor Signalweg, BCR Signaling