ORAI1 Antikörper (AA 202-301)
Kurzübersicht für ORAI1 Antikörper (AA 202-301) (ABIN6145053)
Target
Alle ORAI1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 202-301
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Sequenz
- LKKQPGQPRP TSKPPASGAA ANVSTSGITP GQAAAIASTT IMVPFGLIFI VFAVHFYRSL VSHKTDRQFQ ELNELAEFAR LQDQLDHRGD HPLTPGSHYA
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 202-301 of human ORAI1 (NP_116179.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:200 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))
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Andere Bezeichnung
- ORAI1
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Hintergrund
- The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1).,CRACM1,IMD9,ORAT1,TAM2,TMEM142A,ORAI1,Signal Transduction,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,Neuroscience,Calcium Signaling,ORAI1
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Molekulargewicht
- 25 kDa/32 kDa
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Gen-ID
- 84876
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UniProt
- Q96D31
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Pathways
- T-Zell Rezeptor Signalweg, BCR Signaling
Target
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