ARL6 Antikörper (AA 1-186)

Produktnummer ABIN7143513

Der Kaninchen Polyklonal Anti-ARL6-Antikörper wurde für IHC und ELISA validiert. Er ist geeignet, ARL6 in Proben von Human zu detektieren.

Kurzübersicht für ARL6 Antikörper (AA 1-186) (ABIN7143513)

Target: ARL6 (ADP Ribosylation Factor Like GTPase 6 (ARL6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARL6 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktdetails anti-ARL6 Antikörper

Bindungsspezifität: AA 1-186

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human ADP-ribosylation factor-like protein 6 protein (1-186AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ARL6

Target: ARL6 (ADP Ribosylation Factor Like GTPase 6 (ARL6))

Andere Bezeichnung: ARL6

Hintergrund:

Background: Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia (PubMed:20603001). Together with BBS1, is necessary for correct trafficking of PKD1 to primary cilia (By similarity). Together with the BBSome complex and LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation (PubMed:22072986). May regulate cilia assembly and disassembly and subsequent ciliary signaling events such as the Wnt signaling cascade (PubMed:20207729). Isoform 2 may be required for proper retinal function and organization (By similarity).

Aliases: ADP ribosylation factor like 6 antibody, ADP ribosylation factor like protein 6 antibody, ADP-ribosylation factor-like protein 6 antibody, Arl6 antibody, ARL6_HUMAN antibody, Bardet Biedl syndrome 3 protein antibody, Bardet-Biedl syndrome 3 protein antibody, BBS3 antibody, MGC32934 antibody

UniProt: Q9H0F7