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PDK3 Antikörper (AA 137-406)

Der Kaninchen Polyklonal Anti-PDK3-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, PDK3 in Proben von Human zu detektieren.
Produktnummer ABIN7142007

Kurzübersicht für PDK3 Antikörper (AA 137-406) (ABIN7142007)

Target

Alle PDK3 Antikörper anzeigen
PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))

Reaktivität

  • 31
  • 29
  • 7
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 47
  • 3
Kaninchen

Klonalität

  • 47
  • 3
Polyklonal

Konjugat

  • 32
  • 5
  • 4
  • 3
  • 3
  • 3
Dieser PDK3 Antikörper ist unkonjugiert

Applikation

  • 43
  • 31
  • 17
  • 4
  • 3
  • 3
  • 3
  • 3
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 9
    • 9
    • 7
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 137-406

    Kreuzreaktivität

    Human, Maus

    Aufreinigung

    Antigen Affinity Purified

    Immunogen

    Recombinant Human [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial protein (137-406AA)

    Isotyp

    IgG
  • Applikationshinweise

    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))

    Andere Bezeichnung

    PDK3

    Hintergrund

    Background: Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species.

    Aliases: [Pyruvate dehydrogenase [lipoamide] kinase isozyme 3 mitochondrial antibody, [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3 antibody, CMTX6 antibody, GS1-358P8.4 antibody, mitochondrial antibody, PDK3 antibody, PDK3_HUMAN antibody, Pyruvate dehydrogenase kinase isoenzyme 3 antibody, Pyruvate dehydrogenase kinase isoform 3 antibody, Pyruvate dehydrogenase kinase isozyme 3 antibody, Pyruvate dehydrogenase lipoamide kinase isozyme 3 mitochondrial antibody

    UniProt

    Q15120

    Pathways

    PI3K-Akt Signalweg, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt
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