PDK3 Antikörper (Center)

Produktnummer ABIN2855802

Produktdetails anti-PDK3 Antikörper

Target: PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDK3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)

Kreuzreaktivität: Maus, Huhn, Ratte (Rattus), Rind (Kuh), Xenopus tropicalis

Kreuzreaktivität (Details): Mouse (96 %), Chicken (93 %), Rat (96 %), Bovine (98 %), Xenopus tropicalis (83 %)

Produktmerkmale: Rabbit Polyclonal antibody to PDK3 (pyruvate dehydrogenase kinase, isozyme 3)
PDK3 antibody [N1C2]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human PDK3. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000*

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.4 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu PDK3

Target: PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))

Andere Bezeichnung: PDK3 (PDK3 Produkte)

Synonyme: pdk3 antikoerper, PDK3 antikoerper, 2610001M10Rik antikoerper, AI035637 antikoerper, zgc:158702 antikoerper, pyruvate dehydrogenase kinase 3 antikoerper, pyruvate dehydrogenase kinase, isozyme 3a antikoerper, pyruvate dehydrogenase kinase, isoenzyme 3 antikoerper, fragile site, 5-azacytidine type, common, fra(1)(q12) antikoerper, pyruvate dehydrogenase kinase, isozyme 3b antikoerper, PDK3 antikoerper, Pdk3 antikoerper, pdk3a antikoerper, pdk3 antikoerper, FRA1J antikoerper, pdk3b antikoerper

Hintergrund: Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.

Cellular Localization: Mitochondrion matrix

Molekulargewicht: 47 kDa

Gen-ID: 5165

Pathways: PI3K-Akt Signalweg, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt