GRF2 Antikörper (AA 22-40)

Produktnummer ABIN7140098

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GRF2 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für GRF2 Antikörper (AA 22-40) (ABIN7140098)

Target: GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-GRF2 Antikörper

Bindungsspezifität: AA 22-40

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Peptide sequence from Human Rap guanine nucleotide exchange factor 1 protein (22-40AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu GRF2

Target: GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))

Andere Bezeichnung: RAPGEF1

Hintergrund:

Background: Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth.

Aliases: C3G antibody, C3G protein antibody, CRK SH3 binding GNRP antibody, CRK SH3-binding GNRP antibody, DKFZp781P1719 antibody, GRF 2 antibody, GRF2 antibody, Guanine nucleotide releasing factor 2 (specific for crk proto oncogene) antibody, Guanine nucleotide releasing factor 2 antibody, Guanine nucleotide-releasing factor 2 antibody, OTTHUMP00000064558 antibody, Protein C3G antibody, Rap guanine nucleotide exchange factor (GEF) 1 antibody, Rap guanine nucleotide exchange factor 1 antibody, RAPGEF 1 antibody, RAPGEF1 antibody, RPGF1_HUMAN antibody

UniProt: Q13905

Pathways: Interferon-gamma Pathway, Neurotrophin Signalübertragung, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor