GRF2 Antikörper (AA 844-1095)

Produktnummer ABIN7269849

Produktdetails anti-GRF2 Antikörper

Target: GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))

Bindungsspezifität: AA 844-1095

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Verwendungszweck: RAPGEF1 Rabbit pAb

Sequenz: ARGVAARPGT LHDFHSHEIA EQLTLLDAEL FYKIEIPEVL LWAKEQNEEK SPNLTQFTEH FNNMSYWVRS IIMLQEKAQD RERLLLKFIK IMKHLRKLNN FNSYLAILSA LDSAPIRRLE WQKQTSEGLA EYCTLIDSSS SFRAYRAALS EVEPPCIPYL GLILQDLTFV HLGNPDYIDG KVNFSKRWQQ FNILDSMRCF QQAHYDMRRN DDIINFFNDF SDHLAEEALW ELSLKIKPRN ITRRKTDREE KT

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 844-1095 of human RAPGEF1 (NP_941372.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GRF2

Target: GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))

Andere Bezeichnung: RAPGEF1 (RAPGEF1 Produkte)

Synonyme: C3G antikoerper, GRF2 antikoerper, Link-GEFII antikoerper, 4932418O06Rik antikoerper, Grf2 antikoerper, RAPGEF1 antikoerper, C3G-1 antikoerper, C3G-2 antikoerper, C3g antikoerper, rapgef1 antikoerper, zgc:56372 antikoerper, Rap guanine nucleotide exchange factor 1 antikoerper, Rap guanine nucleotide exchange factor like 1 antikoerper, Rap guanine nucleotide exchange factor (GEF) 1 antikoerper, Rap guanine nucleotide exchange factor 1 S homeolog antikoerper, Rap guanine nucleotide exchange factor (GEF) 1b antikoerper, RAPGEF1 antikoerper, RAPGEFL1 antikoerper, Rapgef1 antikoerper, rapgef1.S antikoerper, rapgef1 antikoerper, rapgef1b antikoerper, Rapgefl1 antikoerper

Hintergrund: This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.,RAPGEF1,C3G,GRF2,Signal Transduction,G protein signaling,Signal Transduction,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,RAPGEF1

Molekulargewicht: 116kDa/120kDa/122kDa

Gen-ID: 2889

UniProt: Q13905

Pathways: Interferon-gamma Pathway, Neurotrophin Signalübertragung, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor