GRF2 Antikörper (AA 536-569)

Produktnummer ABIN6243613

Produktdetails anti-GRF2 Antikörper

Target: GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))

Bindungsspezifität: AA 536-569

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RAPGEF1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 536-569 amino acids from the Central region of human RAPGEF1.

Klon: RB52924

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:2000. WB: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu GRF2

Target: GRF2 (RAPGEF1) (Rap Guanine Nucleotide Exchange Factor (GEF) 1 (RAPGEF1))

Andere Bezeichnung: RAPGEF1 (RAPGEF1 Produkte)

Synonyme: C3G antikoerper, GRF2 antikoerper, Link-GEFII antikoerper, 4932418O06Rik antikoerper, Grf2 antikoerper, RAPGEF1 antikoerper, C3G-1 antikoerper, C3G-2 antikoerper, C3g antikoerper, rapgef1 antikoerper, zgc:56372 antikoerper, Rap guanine nucleotide exchange factor 1 antikoerper, Rap guanine nucleotide exchange factor like 1 antikoerper, Rap guanine nucleotide exchange factor (GEF) 1 antikoerper, Rap guanine nucleotide exchange factor 1 S homeolog antikoerper, Rap guanine nucleotide exchange factor (GEF) 1b antikoerper, RAPGEF1 antikoerper, RAPGEFL1 antikoerper, Rapgef1 antikoerper, rapgef1.S antikoerper, rapgef1 antikoerper, rapgef1b antikoerper, Rapgefl1 antikoerper

Hintergrund: Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS. Plays a role in the establishment of basal endothelial barrier function. Plays a role in nerve growth factor (NGF)-induced sustained activation of Rap1 and neurite outgrowth.

Molekulargewicht: 120548

UniProt: Q13905

Pathways: Interferon-gamma Pathway, Neurotrophin Signalübertragung, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor