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Phospholipase C gamma 1 Antikörper (pTyr771)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Phospholipase C gamma 1 in WB, ELISA und IF. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7139066

Kurzübersicht für Phospholipase C gamma 1 Antikörper (pTyr771) (ABIN7139066)

Target

Alle Phospholipase C gamma 1 (PLCG1) Antikörper anzeigen
Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))

Reaktivität

  • 124
  • 112
  • 103
  • 23
  • 10
  • 9
  • 5
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Human

Wirt

  • 129
  • 27
Kaninchen

Klonalität

  • 118
  • 38
Polyklonal

Konjugat

  • 80
  • 8
  • 6
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
Dieser Phospholipase C gamma 1 Antikörper ist unkonjugiert

Applikation

  • 119
  • 46
  • 38
  • 30
  • 27
  • 20
  • 18
  • 15
  • 15
  • 13
  • 7
  • 4
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • Bindungsspezifität

    • 36
    • 27
    • 13
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr771

    Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

    Immunogen

    Peptide sequence around phosphorylation site of tyrosine 771 (P-D-Y(p)-G-A) derived from Human PLC-g1.

    Isotyp

    IgG
  • Applikationshinweise

    WB:1:500-1:1000, IF:1:100-1:200,

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))

    Andere Bezeichnung

    PLCG1

    Hintergrund

    Background: PLC-gamma is a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase.

    Yue, C. et al. (1998) J. Biol. Chem. 273, 18023-18027.
    Margolis, B. et al. (1989) Cell 57, 1101-1107.
    Yue, C. et al. (2000) J. Biol. Chem. 275, 30220-30225.

    Aliases: 1 phosphatidyl D myo inositol 4 5 bisphosphate antibody, 1 phosphatidylinositol 4 5 bisphosphate phosphodiesterase gamma 1 antibody, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 antibody, Inositoltrisphosphohydrolase antibody, Monophosphatidylinositol phosphodiesterase antibody, NCKAP3 antibody, Phosphatidylinositol phospholipase C antibody, Phosphoinositidase C antibody, Phosphoinositide phospholipase C antibody, Phosphoinositide phospholipase C-gamma-1 antibody, Phospholipase C 148 antibody, Phospholipase C gamma 1 antibody, Phospholipase C-gamma-1 antibody, Phospholipase C-II antibody, PLC gamma 1 antibody, PLC II antibody, PLC-148 antibody, PLC-gamma-1 antibody, PLC-II antibody, PLC1 antibody, PLC148 antibody, Plcg1 antibody, PLCG1_HUMAN antibody, PLCgamma1 antibody

    UniProt

    P19174

    Pathways

    RTK Signalweg, WNT Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Thyroid Hormone Synthesis, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, VEGFR1 Specific Signals, VEGF Signaling
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