PIK3R1 Antikörper (pTyr607)

Produktnummer ABIN7139034

Der Kaninchen Polyklonal Anti-PIK3R1-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, PIK3R1 in Proben von Human zu detektieren.

Kurzübersicht für PIK3R1 Antikörper (pTyr607) (ABIN7139034)

Target: PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIK3R1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PIK3R1 Antikörper

Bindungsspezifität: pTyr607

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of Tyrosine 607(D-Q-Y(p)-S-L) derived from Human PI3-kinase p85-alpha.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:1000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PIK3R1

Target: PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))

Andere Bezeichnung: PIK3R1

Hintergrund:

Background: Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

Aliases: GRB1 antibody, p85 alpha antibody, p85 antibody, P85A_HUMAN antibody, Phosphatidylinositol 3 kinase associated p 85 alpha antibody, Phosphatidylinositol 3 kinase regulatory 1 antibody, Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 1 (p85 alpha) antibody, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha antibody, Phosphatidylinositol 3-kinase regulatory subunit alpha antibody, Phosphoinositide 3 kinase, regulatory subunit 1 (alpha) antibody, PI3 kinase p85 antibody, PI3 kinase p85 subunit alpha antibody, PI3-kinase regulatory subunit alpha antibody, PI3-kinase subunit p85-alpha antibody, PI3K antibody, PI3K p85 antibody, PI3K regulatory subunit alpha antibody, Pik3r1 antibody, PtdIns 3 kinase p85 alpha antibody, PtdIns-3-kinase regulatory subunit alpha antibody, PtdIns-3-kinase regulatory subunit p85-alpha antibody

UniProt: P27986

Pathways: T-Zell Rezeptor Signalweg, Response to Growth Hormone Stimulus, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Hepatitis C, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling, Warburg Effekt