HCLS1 Antikörper (pTyr397)

Produktnummer ABIN7138997

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HCLS1 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für HCLS1 Antikörper (pTyr397) (ABIN7138997)

Target: HCLS1 (Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HCLS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-HCLS1 Antikörper

Bindungsspezifität: pTyr397

Verwendungszweck: Phospho-HCLS1 (Tyr397) Antibody

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of tyrosine 397(G-D-Y(p)-E-E) derived from Human HS1 .

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu HCLS1

Target: HCLS1 (Hematopoietic Cell-Specific Lyn Substrate 1 (HCLS1))

Andere Bezeichnung: HCLS1

Hintergrund:

Background:

Substrate of the antigen receptor-coupled tyrosine kinase. Plays a role in antigen receptor signaling for both clonal expansion and deletion in lymphoid cells. Directly associates with HAX-1, through binding to its C-terminal region. May also be involved in the regulation of gene expression.

Kitamura D., Nucleic Acids Res. 17:9367-9379(1989).
Kalnine N., Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Ota T., Nat. Genet. 36:40-45(2004).

Aliases: Cortactin like antibody, CTTNL antibody, HCLS 1 antibody, Hcls1 antibody, HCLS1_HUMAN antibody, Hematopoietic cell specific Lyn substrate 1 antibody, Hematopoietic cell-specific LYN substrate 1 antibody, Hematopoietic lineage cell-specific protein antibody, HS 1 antibody, HS1 antibody, LckBP1 antibody, OTTHUMP00000215180 antibody, OTTHUMP00000215182 antibody, p75 antibody

UniProt: P14317

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Maintenance of Protein Location