CDK2 Antikörper (pThr160)

Produktnummer ABIN7138780

Dieser Anti-CDK2 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von CDK2 in WB, IHC und ELISA. Geeignet für Human.

Kurzübersicht für CDK2 Antikörper (pThr160) (ABIN7138780)

Target: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-CDK2 Antikörper

Bindungsspezifität: pThr160

Verwendungszweck: Phospho-CDK2 (Thr160) Antibody

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of threonine 160 (T-Y-T(p)-H-E) derived from Human CDK2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CDK2

Target: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Andere Bezeichnung: CDK2

Hintergrund:

Background: Involved in the control of the cell cycle. Interacts with cyclins A, B1, B3, D, or E. Activity of CDK2 is maximal during S phase and G2.

Ukomadu C, et al.(2003) J Biol Chem, 278(7): 4840-6.
Morris MC, et al.(2002)J Biol Chem, 277(26): 23847-53.
Brown NR, et al.(1999)J Biol Chem, 274(13): 8746-56.
Liu Y, et al.(2004) J Biol Chem, 279(6): 4507-14.

Aliases: Cdc2 related protein kinase antibody, cdc2-related protein kinase antibody, CDC28 antibody, CDC2A antibody, Cdk 2 antibody, CDK1 antibody, CDK2 antibody, CDK2_HUMAN antibody, CDKN2 antibody, Cell devision kinase 2 antibody, Cell division protein kinase 2 antibody, Cyclin dependent kinase 2 antibody, cyclin dependent kinase 2-alpha antibody, Cyclin-dependent kinase 2 antibody, kinase Cdc2 antibody, MPF antibody, p33 protein kinase antibody, p33(CDK2) antibody

UniProt: P24941

Pathways: PI3K-Akt Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA