CDC25A Antikörper (pSer76)

Produktnummer ABIN7138695

Der Kaninchen Polyklonal Anti-CDC25A Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, CDC25A in Proben von Human zu detektieren.

Kurzübersicht für CDC25A Antikörper (pSer76) (ABIN7138695)

Target: CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC25A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-CDC25A Antikörper

Bindungsspezifität: pSer76

Verwendungszweck: Phospho-CDC25A (Ser76) Antibody

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of serine 76 (M-G-S(p)-S-E) derived from Human cdc25A.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CDC25A

Target: CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

Andere Bezeichnung: CDC25A

Hintergrund:

Background: Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDC2 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.

Jin J, et al. (2003) Genes 17(24): 3062-74.
Shimuta K, et al. (2002) EMBO J 21(14): 3694-703.

Aliases: Cdc 25a antibody, CDC25A antibody, CDC25A2 antibody, CDC25A2 CAG isoform antibody, Cell division cycle 25 homolog A (S. pombe) antibody, Cell division cycle 25A antibody, Cell division cycle 25A isoform a antibody, Cell division cycle 25A isoform b antibody, D9Ertd393e antibody, Dual specificity phosphatase Cdc25A antibody, M phase inducer phosphatase 1 antibody, M-phase inducer phosphatase 1 antibody, MGC115549 antibody, MPIP1_HUMAN antibody

UniProt: P30304

Pathways: Zellzyklus, Mitotic G1-G1/S Phases, M Phase