CDC25A Antikörper (pThr507)

Produktnummer ABIN3030450

Produktdetails anti-CDC25A Antikörper

Target: CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

Bindungsspezifität: pThr507

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC25A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität (Details): Expected species reactivity: Mouse, Rat, Bovine

Aufreinigung: Antigen affinity purified

Immunogen: This phospho-CDC25A antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pT507 of human CDC25A.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the phospho-CDC25A antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Immunofluorescence: 1:25,Western blot: 1:250-1000,IHC (Paraffin): 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the phospho-CDC25A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu CDC25A

Target: CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

Andere Bezeichnung: Cdc25A (CDC25A Produkte)

Synonyme: cdc25a2 antikoerper, cdc25A antikoerper, sb:cb317 antikoerper, CDC25A2 antikoerper, D9Ertd393e antikoerper, cell division cycle 25A antikoerper, cell division cycle 25B antikoerper, cell division cycle 25A S homeolog antikoerper, CDC25A antikoerper, cdc25a antikoerper, cdc25b antikoerper, Cdc25a antikoerper, cdc25a.S antikoerper

Hintergrund: CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: P30304

Pathways: Zellzyklus, Mitotic G1-G1/S Phases, M Phase