CDC25B Antikörper (pSer323)

Produktnummer ABIN7138555

Dieses Anti-CDC25B-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CDC25B in WB und ELISA. Geeignet für Human.

Kurzübersicht für CDC25B Antikörper (pSer323) (ABIN7138555)

Target: CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC25B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CDC25B Antikörper

Bindungsspezifität: pSer323

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of serine 323 (S-P-S(p)-M-P) derived from Human CDC25B.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:3000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CDC25B

Target: CDC25B (Cell Division Cycle 25 Homolog B (S. Pombe) (CDC25B))

Andere Bezeichnung: CDC25B

Hintergrund:

Background: Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.

Aliases: AI604853 antibody, Cdc 25B antibody, Cdc25b antibody, CDC25HU2 antibody, Cdc25m2 antibody, Cell division cycle 25 homolog B antibody, Cell division cycle 25B antibody, Cell division cycle 25B isoform 1 antibody, Cell division cycle 25B isoform 2 antibody, Cell division cycle 25B isoform 3 antibody, Cell division cycle 25B isoform 4 antibody, Cell division cycle 25B isoform 5 antibody, Dual specificity phosphatase Cdc25B antibody, EC 3.1.3.48 antibody, M phase inducer phosphatase 2 antibody, M-phase inducer phosphatase 2 antibody, MPIP2_HUMAN antibody

UniProt: P30305

Pathways: Zellzyklus, M Phase, Autophagie