PHLPP1 Antikörper

Produktnummer ABIN7130610

Der Kaninchen Polyklonal anti-PHLPP1 Antikörper wird verwendet zum Nachweis von PHLPP1 in Proben von Human. Er wurde validiert für ELISA und IHC.

Kurzübersicht für PHLPP1 Antikörper (ABIN7130610)

Target: PHLPP1 (PH Domain and Leucine Rich Repeat Protein Phosphatase 1 (PHLPP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHLPP1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-PHLPP1 Antikörper

Verwendungszweck: PHLPP1 Antibody

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of Human PHLPP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PHLPP1

Target: PHLPP1 (PH Domain and Leucine Rich Repeat Protein Phosphatase 1 (PHLPP1))

Andere Bezeichnung: PHLPP1

Hintergrund:

Background: This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.

Aliases: hSCOP antibody, KIAA0606 antibody, PH domain and leucine rich repeat protein phosphatase antibody, PH domain leucine rich repeat containing protein phosphatase antibody, PH domain leucine rich repeat protein phosphatase antibody, PH domain leucine-rich repeat-containing protein phosphatase 1 antibody, PH domain-containing family E member 1 antibody, PHLP1_HUMAN antibody, PHLPP antibody, Phlpp1 antibody, Pleckstrin homology domain containing family E (with leucine rich repeats) member 1 antibody, Pleckstrin homology domain containing family E protein 1 antibody, Pleckstrin homology domain-containing family E member 1 antibody, PLEKHE 1 protein antibody, PLEKHE1 antibody, SCN circadian oscillatory protein antibody, SCOP antibody, Suprachiasmatic nucleus circadian oscillatory protein antibody, Suprachiasmatic nucleus circadian protein antibody

UniProt: O60346

Pathways: PI3K-Akt Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung