Rekombinanter CD46 Antikörper
Kurzübersicht für Rekombinanter CD46 Antikörper (ABIN7127403)
Target
Alle CD46 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Kreuzreaktivität
- Human
-
Aufreinigung
- Affinity-chromatography
-
Immunogen
- A synthesized peptide derived from human CD46
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200,
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C,-80 °C
-
Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- CD46
-
Andere Bezeichnung
- CD46
-
Hintergrund
-
Background: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity.
Aliases: Membrane cofactor protein (TLX) (Trophoblast leukocyte common antigen) (CD antigen CD46), CD46, MCP MIC10
-
UniProt
- P15529
-
Pathways
- Regulation of Actin Filament Polymerization
Target
-