Rekombinanter ATG5 Antikörper (AA 1-119)

Produktnummer ABIN7127196

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch ATG5 in ELISA und Coat. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Rekombinanter ATG5 Antikörper (AA 1-119) (ABIN7127196)

Target: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ATG5 Antikörper ist unkonjugiert

Applikation: ELISA, Coating (Coat)

Produktdetails anti-ATG5 Antikörper

Bindungsspezifität: AA 1-119

Spezifität: The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. The ATG5 protein is essential for autophagy, a process that is usually beneficial for cells to self-degrade their own components when they are no longer useful.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant fragment of human ATG5 protein (around aa 1-119) (exact sequence is proprietary)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Known_Application: ELISA (For coating, order antibody without BSA),Optimal dilution for a specific application should be determined.

Positive_Control: K562, U-87, A431, THP-1, PANC-1, Raji or HeLa cells. Ovary, Endometrium, Colon or Duodenum.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu ATG5

Target: ATG5 (ATG5 Autophagy Related 5 (ATG5))

Andere Bezeichnung: ATG5

Hintergrund: APG5 autophagy 5 like (APG5L), Apoptosis-specific protein (ASP), ATG5, Autophagy related 5, hAPG5,ATG5 (Autophagy Marker)
Cellular localisation: Cytoplasmic

Molekulargewicht: 32kDa

Gen-ID: 9474, 486063

UniProt: Q9H1Y0

Pathways: Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagie