SOCS6 Antikörper
Kurzübersicht für SOCS6 Antikörper (ABIN7119606)
Target
Alle SOCS6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- SOCS6 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- suppressor of cytokine signaling 6
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000, IHC: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))
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Andere Bezeichnung
- SOCS6
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Hintergrund
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Synonyms: Suppressor of cytokine signaling 6 (SOCS-6)|Cytokine-inducible SH2 protein 4 (CIS-4)|Suppressor of cytokine signaling 4 (SOCS-4)|SOCS6|CIS4|SOCS4
Background: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS(Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins(By similarity). Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor.
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Molekulargewicht
- 70 kDa
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Gen-ID
- 9306
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UniProt
- O14544
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Pathways
- JAK-STAT Signalweg, Carbohydrate Homeostasis
Target
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