SQSTM1 Antikörper (AA 1-440)
Kurzübersicht für SQSTM1 Antikörper (AA 1-440) (ABIN7118890)
Target
Alle SQSTM1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-440
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Verwendungszweck
- SQSTM1 antibody
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Aufreinigung
- protein A+G purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: 1-440aa
Immunogen: sequestosome 1
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Isotyp
- IgG2a
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Applikationshinweise
- WB: 1:1000 - 1:4000, IHC: 1:50 - 1:500, IF: 1:20 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- SQSTM1 (Sequestosome 1 (SQSTM1))
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Andere Bezeichnung
- SQSTM1
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Hintergrund
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Synonyms: Sequestosome-1|EBI3-associated protein of 60 kDa (EBIAP, p60)|Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa|Ubiquitin-binding protein p62|SQSTM1|ORCA|OSIL
Background: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
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Molekulargewicht
- 62 kDa
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Gen-ID
- 8878
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UniProt
- Q13501
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Pathways
- NF-kappaB Signalweg, Neurotrophin Signalübertragung, Autophagie
Target
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