RNF7 Antikörper
Kurzübersicht für RNF7 Antikörper (ABIN7118661)
Target
Alle RNF7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- RNF7 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- ring finger protein 7
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000, IF: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- RNF7 (Ring Finger Protein 7 (RNF7))
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Andere Bezeichnung
- RNF7
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Hintergrund
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Synonyms: RING-box protein 2 (Rbx2)|CKII beta-binding protein 1 (CKBBP1)|RING finger protein 7|Regulator of cullins 2|Sensitive to apoptosis gene protein|RNF7|RBX2|ROC2|SAG
Background: Probable component of the SCF(SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents.
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Molekulargewicht
- 13 kDa
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Gen-ID
- 9616
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UniProt
- Q9UBF6
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Pathways
- Positive Regulation of Endopeptidase Activity
Target
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