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RNF7 Antikörper

RNF7 Reaktivität: Human, Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7075471
  • Target Alle RNF7 Antikörper anzeigen
    RNF7 (Ring Finger Protein 7 (RNF7))
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 21
    • 1
    Kaninchen
    Klonalität
    • 22
    Polyklonal
    Konjugat
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RNF7 Antikörper ist unkonjugiert
    Applikation
    • 10
    • 10
    • 4
    • 4
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Kreuzreaktivität
    Human, Ratte
    Aufreinigung
    Affinity purification
    Immunogen
    KLH conjugated Synthetic peptide corresponding to Mouse RNF7
  • Applikationshinweise
    IHC/IF (H,M,R) 1:500-1:2000/1:500-1:3000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    RNF7 (Ring Finger Protein 7 (RNF7))
    Andere Bezeichnung
    RNF7 (RNF7 Produkte)
    Synonyme
    CKBBP1 antikoerper, ROC2 antikoerper, SAG antikoerper, Rbx2 antikoerper, ring finger protein 7 antikoerper, RNF7 antikoerper, Rnf7 antikoerper
    Hintergrund
    The RNF7 is probable a component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents.
    Gen-ID
    19823
    NCBI Accession
    NP_001298064
    UniProt
    Q9WTZ1
    Pathways
    Positive Regulation of Endopeptidase Activity
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