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RNF7 Antikörper

RNF7 Reaktivität: Human IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7263303
  • Target Alle RNF7 Antikörper anzeigen
    RNF7 (Ring Finger Protein 7 (RNF7))
    Reaktivität
    • 22
    • 11
    • 3
    Human
    Wirt
    • 21
    • 1
    Kaninchen
    Klonalität
    • 22
    Polyklonal
    Konjugat
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RNF7 Antikörper ist unkonjugiert
    Applikation
    • 10
    • 10
    • 5
    • 4
    • 1
    • 1
    Immunofluorescence (IF)
    Produktmerkmale
    Polyclonal Antibody
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein of human RNF7 (NP_055060.1).
    Isotyp
    IgG
    Top Product
    Discover our top product RNF7 Primärantikörper
  • Applikationshinweise
    IF 1:20-1:50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    RNF7 (Ring Finger Protein 7 (RNF7))
    Andere Bezeichnung
    RNF7 (RNF7 Produkte)
    Synonyme
    CKBBP1 antikoerper, ROC2 antikoerper, SAG antikoerper, Rbx2 antikoerper, ring finger protein 7 antikoerper, RNF7 antikoerper, Rnf7 antikoerper
    Hintergrund
    The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.
    Gen-ID
    9616
    UniProt
    Q9UBF6
    Pathways
    Positive Regulation of Endopeptidase Activity
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