RNF7 Antikörper (N-Term)

Produktnummer ABIN6242612

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RNF7 in WB und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für RNF7 Antikörper (N-Term) (ABIN6242612)

Target: RNF7 (Ring Finger Protein 7 (RNF7))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB52911

Produktdetails anti-RNF7 Antikörper

Bindungsspezifität: AA 25-57, N-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This RNF7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 25-57 amino acids from the N-terminal region of human RNF7.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:8000. IHC-P: 1:25

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu RNF7

Target: RNF7 (Ring Finger Protein 7 (RNF7))

Andere Bezeichnung: RNF7

Hintergrund: Probable component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents.

Molekulargewicht: 12683

UniProt: Q9UBF6

Pathways: Positive Regulation of Endopeptidase Activity