ARHGEF4 Antikörper
Kurzübersicht für ARHGEF4 Antikörper (ABIN7118493)
Target
Alle ARHGEF4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- ARHGEF4 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- Rho guanine nucleotide exchange factor(GEF) 4
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Isotyp
- IgG
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anti-rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) (N-Term) antibody
ARHGEF4 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) (AA 143-271) antibodyARHGEF4 Reaktivität: Human WB, FACS Wirt: Maus Monoclonal ARHGEF-08 unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) (AA 143-271) antibody (PE)ARHGEF4 Reaktivität: Human ICFC Wirt: Maus Monoclonal ARHGEF-08 PE
anti-rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) (N-Term) antibodyVerified ARHGEF4 Reaktivität: Human WB, ELISA Wirt: Ziege Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) (AA 573-599), (C-Term) antibodyARHGEF4 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB37410 unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) (AA 1-100) antibodyARHGEF4 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) (Internal Region) antibodyARHGEF4 Reaktivität: Human, Maus, Ratte WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) (AA 51-100) antibodyARHGEF4 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB: 1:500-1:2000, IHC: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- ARHGEF4 (rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4))
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Andere Bezeichnung
- ARHGEF4
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Hintergrund
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Synonyms: Rho guanine nucleotide exchange factor 4|APC-stimulated guanine nucleotide exchange factor 1 (Asef, Asef1)|ARHGEF4|KIAA1112
Background: Acts as guanine nucleotide exchange factor(GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
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Molekulargewicht
- 72 kDa
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Gen-ID
- 50649
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UniProt
- Q9NR80
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Pathways
- Neurotrophin Signalübertragung
Target
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