PRKAA2 Antikörper

Produktnummer ABIN7117965

Dieses Anti-PRKAA2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PRKAA2 in WB, ELISA, IHC, IF und IP. Geeignet für Human, Maus und Ratte.

Kurzübersicht für PRKAA2 Antikörper (ABIN7117965)

Target: PRKAA2 (Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRKAA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Produktdetails anti-PRKAA2 Antikörper

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: protein kinase, AMP-activated, alpha 2 catalytic subunit

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:10000, IHC: 1:20-1:200, IF: 1:10-1:100, IP:1:500-1:5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Haltbarkeit: 12 months

Details zu PRKAA2

Target: PRKAA2 (Protein Kinase, AMP-Activated, alpha 2 Catalytic Subunit (PRKAA2))

Andere Bezeichnung: AMPK alpha 2

Hintergrund: Synonyms:AMPK, AMPK alpha 2, AMPK subunit alpha 2, AMPK2, PRKAA, PRKAA2 Background:PRKAA2(protein kinase, AMP-activated, alpha 2 catalytic subunit), also named as AMPKA2, AMPK, PRKAA, AMPK2, belonogs to the CAMK Ser/Thr protein kinase family and SNF1 subfamily. PRKAA2 is an αβγ heterotrimer that is activated by low cellular energy status, such as decreases in both the ATP/AMP ratio and the phosphocreatine content and it is a glycogen synthase kinase, phosphorylating Ser7 at the NH2 terminus, which decreases glycogen synthase activity(PMID:14532170). The protein can be ubiquitinated(PMID:21224036).

Molekulargewicht: 62 kDa

Gen-ID: 5563

UniProt: P54646

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, Warburg Effekt