ORAI1 Antikörper
Kurzübersicht für ORAI1 Antikörper (ABIN7117125)
Target
Alle ORAI1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Verwendungszweck
- ORAI1 antibody
-
Aufreinigung
- Immunogen affinity purified
-
Reinheit
- ≥95 % as determined by SDS-PAGE
-
Immunogen
- ORAI calcium release-activated calcium modulator 1
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB: 1:500-1:1000, IF: 1:10-1:100
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze / thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- -20°C for 12 months
-
Haltbarkeit
- 12 months
-
-
- ORAI1 (ORAI Calcium Release-Activated Calcium Modulator 1 (ORAI1))
-
Andere Bezeichnung
- ORAI1
-
Hintergrund
-
Synonyms: Calcium release-activated calcium channel protein 1|Protein orai-1|Transmembrane protein 142A|ORAI1|CRACM1|TMEM142A
Background: Ca(2+) release-activated Ca(2+)(CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1. CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT(PubMed:16582901).
-
Molekulargewicht
- 45 kDa
-
Gen-ID
- 84876
-
UniProt
- Q96D31
-
Pathways
- T-Zell Rezeptor Signalweg, BCR Signaling
Target
-