NSUN2 Antikörper
Kurzübersicht für NSUN2 Antikörper (ABIN7116925)
Target
Alle NSUN2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- NSUN2 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- NOL1/NOP2/Sun domain family, member 2
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- NSUN2 (NOP2/Sun Domain Family, Member 2 (NSUN2))
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Andere Bezeichnung
- NSUN2
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Hintergrund
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Synonyms: RNA cytosine C(5)-methyltransferase NSUN2|Myc-induced SUN domain-containing protein (Misu)|NOL1/NOP2/Sun domain family member 2|Substrate of AIM1/Aurora kinase B|mRNA cytosine C(5)-methyltransferase|tRNA cytosine C(5)-methyltransferase|tRNA methyltransferase 4 homolog (hTrm4)|NSUN2|SAKI|TRM4
Background: RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. Methylates cytosine to 5-methylcytosine(m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. May act downstream of Myc to regulate epidermal cell growth and proliferation. Required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.
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Molekulargewicht
- 90-100 kDa
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Gen-ID
- 54888
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UniProt
- Q08J23
Target
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