MALT1 Antikörper
Kurzübersicht für MALT1 Antikörper (ABIN7116527)
Target
Alle MALT1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- MALT1 antibody
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Aufreinigung
- Protein A+G purification
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- mucosa associated lymphoid tissue lymphoma translocation gene 1
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Isotyp
- IgG2a
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Applikationshinweise
- WB: 1:500-1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))
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Andere Bezeichnung
- MALT1
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Hintergrund
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Synonyms: Mucosa-associated lymphoid tissue lymphoma translocation protein 1|MALT lymphoma-associated translocation|Paracaspase|MALT1|MLT
Background: Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion.
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Molekulargewicht
- 90 kDa
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Gen-ID
- 10892
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UniProt
- Q9UDY8
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Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteine
Target
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