IL-6 Receptor Antikörper
Kurzübersicht für IL-6 Receptor Antikörper (ABIN7115473)
Target
Alle IL-6 Receptor (IL6R) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- IL6R antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: P08887-1,229-468
Immunogen: interleukin 6 receptor
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:1000, IHC: 1:50-1:200, IP: 1:500-1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
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Andere Bezeichnung
- IL6R
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Hintergrund
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Synonyms: Interleukin-6 receptor subunit alpha (IL-6 receptor subunit alpha, IL-6R subunit alpha, IL-6R-alpha, IL-6RA)|IL-6R 1|Membrane glycoprotein 80 (gp80)|Soluble interleukin-6 receptor subunit alpha (sIL6R)|IL6R
Background: Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis. Low concentration of a soluble form of IL6 receptor acts as an agonist of IL6 activity.
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Molekulargewicht
- 80 kDa
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Gen-ID
- 3570
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UniProt
- P08887
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Pathways
- JAK-STAT Signalweg, Autophagie, Growth Factor Binding, Cancer Immune Checkpoints
Target
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