IRF9 Antikörper
Kurzübersicht für IRF9 Antikörper (ABIN7115377)
Target
Alle IRF9 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- IRF9 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- interferon regulatory factor 9
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:50-1:500, IF: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- IRF9 (Interferon Regulatory Factor 9 (IRF9))
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Andere Bezeichnung
- IRF9
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Hintergrund
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Synonyms: Interferon regulatory factor 9 (IRF-9)|IFN-alpha-responsive transcription factor subunit|ISGF3 p48 subunit|Interferon-stimulated gene factor 3 gamma (ISGF-3 gamma)|Transcriptional regulator ISGF3 subunit gamma|IRF9|ISGF3G
Background: Transcription factor that mediates signaling by type I IFNs(IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases(TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element(ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
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Molekulargewicht
- 48 kDa
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Gen-ID
- 10379
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UniProt
- Q00978
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Pathways
- JAK-STAT Signalweg, Interferon-gamma Pathway, Hepatitis C
Target
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