IFNAR2 Antikörper
Kurzübersicht für IFNAR2 Antikörper (ABIN7115355)
Target
Alle IFNAR2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- IFNAR2 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- interferon(alpha, beta and omega) receptor 2
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))
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Andere Bezeichnung
- IFNAR2
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Hintergrund
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Synonyms: Interferon alpha/beta receptor 2 (IFN-R-2, IFN-alpha binding protein, IFN-alpha/beta receptor 2)|Interferon alpha binding protein|Type I interferon receptor 2|IFNAR2|IFNABR|IFNARB
Background: Associates with IFNAR1 to form the type I interferon receptor. Receptor for interferons alpha and beta. Involved in IFN-mediated STAT1, STAT2 and STAT3 activation(PubMed:26424569). Isoform 1 and isoform 2 are directly involved in signal transduction due to their association with the TYR kinase, JAK1(PubMed:8181059, PubMed:7665574, PubMed:7759950). Isoform 3 is a potent inhibitor of type I IFN receptor activity(PubMed:7759950).
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Molekulargewicht
- 58-66 kDa
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Gen-ID
- 3455
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UniProt
- P48551
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Pathways
- JAK-STAT Signalweg, Hepatitis C
Target
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