IFNAR2 Antikörper (Center)

Produktnummer ABIN2856183

Produktdetails anti-IFNAR2 Antikörper

Target: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFNAR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktmerkmale: Rabbit Polyclonal antibody to IFNAR2 (interferon (alpha, beta and omega) receptor 2)
IFNAR2 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human IFNAR2. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-IFNAR2 Antikörper (ABIN2856183)

Shirozu, Iwano, Ogiso, Suzuki, Balboula, Bai, Kawahara, Kimura, Takahashi, Rulan, Kim, Yanagawa, Nagano, Imakawa, Takahashi: "Estrous cycle stage-dependent manner of type I interferon-stimulated genes induction in the bovine endometrium." in: The Journal of reproduction and development, Vol. 63, Issue 3, pp. 211-220, (2018) (PubMed).

Details zu IFNAR2

Target: IFNAR2 (Interferon alpha/beta Receptor 2 (IFNAR2))

Andere Bezeichnung: IFNAR2 (IFNAR2 Produkte)

Synonyme: AI747302 antikoerper, Ifnar-2 antikoerper, IFN-R antikoerper, IFN-alpha-REC antikoerper, IFNABR antikoerper, IFNARB antikoerper, IFN-R-2 antikoerper, IFNBR antikoerper, interferon alpha and beta receptor subunit 2 antikoerper, interferon (alpha and beta) receptor 2 antikoerper, IFNAR2 antikoerper, Ifnar2 antikoerper

Hintergrund: The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene.

Cellular Localization: Membrane, Single-pass type I membrane protein

Molekulargewicht: 58 kDa

Gen-ID: 3455

Pathways: JAK-STAT Signalweg, Hepatitis C