Der Kaninchen Polyklonal Anti-C5AR1-Antikörper wurde für WB, ELISA, IHC, IF und IP validiert. Er ist geeignet, C5AR1 in Proben von Human, Maus und Ratte zu detektieren.
Synonyms:C5AR, C5R1 Background:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a(PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events(PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production(PubMed:10636859, PubMed:15153520).