BAX Antikörper (AA 1-192)
Kurzübersicht für BAX Antikörper (AA 1-192) (ABIN7111962)
Target
Alle BAX Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-192
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Verwendungszweck
- BAX antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: 1-192aa
Immunogen: BCL2-associated X protein
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Isotyp
- IgG
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anti-BCL2-Associated X Protein (BAX) (AA 84-175) antibody
BAX Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Kaninchen, Huhn, Zebrafisch (Danio rerio) WB, ELISA, FACS, IP, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 1-100) antibodyBAX Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 41-76) antibodyBAX Reaktivität: Human, Maus WB, FACS Wirt: Kaninchen Polyclonal RB0952 unconjugated
anti-BCL2-Associated X Protein (BAX) (N-Term) antibodyBAX Reaktivität: Human, Maus, Ratte, Affe, Schwein, Rind (Kuh), Kaninchen, Hund, Huhn, Schaf, Hamster, Pferd, Meerschweinchen, Ziege, Avian, Cat, Esel WB, IF Wirt: Ziege Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 1-158) antibodyBAX Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 13-160) antibodyBAX Reaktivität: Human IHC, ELISA Wirt: Maus Monoclonal 4H9B11 unconjugated
anti-BCL2-Associated X Protein (BAX) antibodyBAX Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 2G6B2 unconjugated
anti-BCL2-Associated X Protein (BAX) antibodyBAX Reaktivität: Human IHC, ELISA, FACS Wirt: Maus Monoclonal 2D8H2 unconjugated
anti-BCL2-Associated X Protein (BAX) (AA 1-192) antibodyBAX Reaktivität: Human WB, ELISA, IF, IHC (p), PLA Wirt: Maus Monoclonal 1F5-1B7 unconjugated
anti-BCL2-Associated X Protein (BAX) (N-Term) antibodyBAX Reaktivität: Human, Schwein, Rind (Kuh), Hund WB, IHC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB: 1:1000-1:10000, IP: 1:1000-1:10000, IHC: 1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- BAX (BCL2-Associated X Protein (BAX))
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Andere Bezeichnung
- BAX
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Hintergrund
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Synonyms: Apoptosis regulator BAX|Bcl-2-like protein 4 (Bcl2-L-4)|BAX|BCL2L4
Background: BAX, also named as BCL2L4, is a pro-apoptotic member of the Bcl-2 protein family, which plays a pivotal role in controlling cell life and death. Bax largely localizes to the cytoplasm of healthy cells, but accumulates on the outer mitochondrial membrane upon apoptosis induction(PMID: 9108035). BAX can commit a cell to apoptosis by translocation from the cytosol to the mitochondria and permeabilization of the outer mitochondrial membrane, which leads to the release of cytochrome c from mitochondria(PMID: 21763611). The expression of BAX is upregulated by the tumor suppressor protein p53, and BAX has been shown to be involved in p53-mediated apoptosis(PMID: 8183579).
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Molekulargewicht
- 21 kDa
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Gen-ID
- 581
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UniProt
- Q07812
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Pathways
- p53 Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
Target
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