RIPK3 Antikörper

Produktnummer ABIN7091641

Der Maus Monoklonal Anti-RIPK3-Antikörper wurde für WB validiert. Er ist geeignet, RIPK3 in Proben von Human zu detektieren.

Kurzübersicht für RIPK3 Antikörper (ABIN7091641)

Target: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RIPK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: D11F6

Produktdetails anti-RIPK3 Antikörper

Homologie: Human

Immunogen: Recombinant human RIPK3.

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu RIPK3

Target: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Andere Bezeichnung: RIPK3

Hintergrund:

Synonyms: Receptor interacting protein 3, Receptor interacting serine threonine kinase 3, Receptor interacting serine/threonine protein kinase 3, Receptor-interacting protein 3, Receptor-interacting serine/threonine-protein kinase 3, RIP 3, RIP like protein kinase 3, RIP-3, RIP-like protein kinase 3, RIPK 3, RIPK3_HUMAN.

Background: Essential for programmed necrosis in response to death-inducing TNF-alpha family members. Upon induction of necrosis, RIPK3 interacts with, and phosphorylates RIPK1 to form a necrosis-inducing complex. RIPK3 binds to and enhances the activity of three metabolic enzymes: GLUL, GLUD1, and PYGL. These metabolic enzymes may eventually stimulate the tricarboxylic acid cycle and oxidative phosphorylation, which could result in enhanced ROS production.

Gen-ID: 11035

UniProt: Q9Y572

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades