KLRK1 Antikörper

Produktnummer ABIN7091315

Dieses Anti-KLRK1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von KLRK1 in WB, ELISA, ICC, IHC (fro), IF und IHC (p). Geeignet für Maus.

Kurzübersicht für KLRK1 Antikörper (ABIN7091315)

Target: KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLRK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-KLRK1 Antikörper

Kreuzreaktivität: Maus

Homologie: Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse NKG2D

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF()
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu KLRK1

Target: KLRK1 (Killer Cell Lectin-Like Receptor Subfamily K, Member 1 (KLRK1))

Andere Bezeichnung: NKG2D

Hintergrund:

Synonyms: KLRK1, natural killer cell group 2D, NKG2-D isoform b, Klrk1, Nkrp2, NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, NK cell receptor D, Killer cell lectin-like receptor subfamily K, NK lectin-like receptor, CD314, CD 314, CD314 antigen, D12S2489E, Killer cell lectin like receptor subfamily K member 1, Killer cell lectin-like receptor subfamily K member 1, KLR, Klrk1, NKG2 D activating NK receptor, NKG2 D type II integral membrane protein, NKG2-D-activating NK receptor, NKG2D_HUMAN, NKLLR, NKR P2, Nkrp2.

Background: Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes.

Gen-ID: 27007

UniProt: O54709

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process