EIF2AK2 Antikörper

Produktnummer ABIN7091088

Dieser Maus Monoklonal Antikörper detektiert spezifisch EIF2AK2 in WB, IF und ICC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für EIF2AK2 Antikörper (ABIN7091088)

Target: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser EIF2AK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: R5D3

Produktdetails anti-EIF2AK2 Antikörper

Homologie: Human

Immunogen: Recombinant human EIF2AK2.

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IF()
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu EIF2AK2

Target: EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))

Andere Bezeichnung: EIF2AK2

Hintergrund:

Synonyms: double-stranded RNA-dependent Protein Kinase, interferon-induced, double-stranded RNA-activated protein kinase isoform a, protein kinase, interferon-inducible double stranded RNA dependent, interferon-inducible elF2alpha kinase, double stranded RNA activated protein kinase, p68 kinase, eIF-2A protein kinase 2, P1/eIF-2A protein kinase, protein kinase RNA-activated, interferon-inducible RNA-dependent protein kinase, EIF2AK1, MGC126524, PKR, PRKRv, E2AK2_HUMAN.

Background: Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection.

Gen-ID: 5610

UniProt: P19525

Pathways: DNA Reparatur, ER-Nucleus Signaling, Hepatitis C