EPH Receptor B4 Antikörper

Produktnummer ABIN7091064

Dieses Maus Monoklonal-Antikörper erkennt spezifisch EPH Receptor B4 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für EPH Receptor B4 Antikörper (ABIN7091064)

Target: EPH Receptor B4 (EPHB4)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser EPH Receptor B4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: B12M1

Produktdetails anti-EPH Receptor B4 Antikörper

Homologie: Human

Immunogen: Recombinant human EPHB4.

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu EPH Receptor B4

Target: EPH Receptor B4 (EPHB4)

Andere Bezeichnung: EPHB4

Hintergrund:

Synonyms: Eph receptor B4, EPHB4_HUMAN, Ephrin type-B receptor 4, Hepatoma Transmembrane Kinase, HTK, MYK1, TYRO11, Tyrosine-protein kinase receptor HTK, Tyrosine-protein kinase TYRO11.

Background: Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis.

Gen-ID: 2050

UniProt: P54760

Pathways: RTK Signalweg