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BAX Antikörper (AA 101-192) (HRP)

Der Kaninchen Polyklonal Anti-BAX-Antikörper wurde für WB validiert. Er ist geeignet, BAX in Proben von Maus und Ratte zu detektieren.
Produktnummer ABIN7090786

Kurzübersicht für BAX Antikörper (AA 101-192) (HRP) (ABIN7090786)

Target

Alle BAX Antikörper anzeigen
BAX (BCL2-Associated X Protein (BAX))

Reaktivität

  • 243
  • 154
  • 137
  • 46
  • 32
  • 27
  • 24
  • 18
  • 16
  • 11
  • 9
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Maus, Ratte

Wirt

  • 158
  • 100
  • 3
  • 1
Kaninchen

Klonalität

  • 168
  • 94
Polyklonal

Konjugat

  • 139
  • 13
  • 10
  • 9
  • 7
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser BAX Antikörper ist konjugiert mit HRP

Applikation

  • 224
  • 94
  • 81
  • 70
  • 52
  • 52
  • 49
  • 47
  • 35
  • 22
  • 11
  • 8
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 32
    • 26
    • 18
    • 17
    • 15
    • 12
    • 10
    • 9
    • 8
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-192

    Kreuzreaktivität

    Maus, Ratte

    Homologie

    Dog,Cow,Sheep,Pig,Horse,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Bax

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Target

    BAX (BCL2-Associated X Protein (BAX))

    Andere Bezeichnung

    Bax

    Hintergrund

    Synonyms: apoptosis regulator BAX, Apoptosis regulator BAX cytoplasmic isoform beta, Apoptosis regulator BAX membrane isoform alpha, Bax isoform psi, BAX protein cytoplasmic isoform delta, Bax protein cytoplasmic isoform delta. antibody Bax protein cytoplasmic isoform gamma, Bax zeta, Bax-protein, Bcl-2-like protein 4, BCL2 associated X protein, BCL2L4, BAX_HUMAN, Bcl2-L-4

    Background: The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. [provided by RefSeq, Jul 2008].

    Gen-ID

    581

    UniProt

    Q07812

    Pathways

    p53 Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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