BCL10 Antikörper (AA 1-130)

Produktnummer ABIN7090778

Dieses Anti-BCL10-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von BCL10 in WB und IHC (p). Geeignet für Human.

Kurzübersicht für BCL10 Antikörper (AA 1-130) (ABIN7090778)

Target: BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BCL10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: G56

Produktdetails anti-BCL10 Antikörper

Bindungsspezifität: AA 1-130

Homologie: Human

Immunogen: KLH conjugated synthetic peptide derived from human BCL10

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu BCL10

Target: BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

Andere Bezeichnung: BCL10

Hintergrund:

Synonyms: Bcl-10, B cell CLL/lymphoma 10, B cell lymphoma/leukemia10, B-cell leukemia/lymphoma 10, Bcl 10, c E10, c-E10, C81403, CARD containing apoptotic signaling protein, CARD containing molecule enhancing NF kappa B, CARD containing molecule enhancing NF kB, CARD containing molecule enhancing NFkB, CARD containing proapoptotic protein, CARD like apoptotic protein, CARMEN, Caspase recruiting domain containing protein, cCARMEN, cE 10, cE10, CED 3/ICH 1 prodomain homologous E10 like regulator, CED3/ICH1 prodomain homologous E10 like regulator, Cellular E10, Cellular homolog of vCARMEN, CIPER, CLAP, hCLAP, Mammalian CARD containing adapter molecule E10, mE 10, mE10, R-RCD1, BCL10_HUMAN.

Background: Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1.

Gen-ID: 8915

UniProt: O95999

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteine