Rekombinanter C5AR1 Antikörper (AA 1-31)

Produktnummer ABIN7072651

Dieses Kaninchen Chimeric-Antikörper erkennt spezifisch C5AR1 in WB, FACS, ELISA, IP, Func und BP. Er zeigt eine Reaktivität gegenüber Human, Rind (Kuh), Kaninchen und Frettchen.

Kurzübersicht für Rekombinanter C5AR1 Antikörper (AA 1-31) (ABIN7072651)

Target: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Rind (Kuh), Kaninchen, Frettchen

Wirt: Kaninchen

Klonalität: Chimeric

Konjugat: Dieser C5AR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunoprecipitation (IP), Functional Studies (Func), Blocking Peptide (BP)

Klon: S5-1

Produktdetails anti-C5AR1 Antikörper

Bindungsspezifität: AA 1-31

Verwendungszweck: Anti-C5aR [S5/1], Rabbit IgG, kappa

Spezifität: S5/1 antibody recognizes the C5aR (CD88) protein, a 43 kDa receptor of C5a component of the complement cascade.

Kreuzreaktivität: Rind (Kuh), Frettchen, Kaninchen

Produktmerkmale:

Original Species of Ab: Mouse

Original Format of Ab: IgG2a

Aufreinigung: Protein A affinity purified

Immunogen: This antibody was raised by immunizing mice with a synthetic peptide corresponding to C5a-R, amino acids: 1-31 (N terminal).

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: S5/1 antibody inhibits C5a binding to its receptor C5aR (Oppermann et al., 1993). Furthermore, this antibody has been widely applied in the detection and analysis of C5aR via various methods. For instance, it was used in a flow cytometric study on peripheral blood lymphocytes where it was shown to bind to monocytes and granulocytes (Oppermann et al., 1993). It was also utilized in the Western blot experiments comparing C5aR expression in different groups of mice (Panayiotou et al., 2017). S5/1 was also successfull in labelling C5aR in the paraffin-embedded immunohistochemical samples of umbilical arteries (Fortin et al., 2002).

Kommentare:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Details zu C5AR1

Target: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Andere Bezeichnung: C5aR

Hintergrund: CD88, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR

UniProt: P21730

Pathways: Komplementsystem