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Rekombinanter Tyrosinase-Related Protein 1 Antikörper

Dieses Anti-Tyrosinase-Related Protein 1-Antikörper ist ein Kaninchen Chimeric-Antikörper zur Detektion von Tyrosinase-Related Protein 1 in IF, FACS, WB, ELISA, IHC (fro) und IP. Geeignet für Human.
Produktnummer ABIN7072221

Kurzübersicht für Rekombinanter Tyrosinase-Related Protein 1 Antikörper (ABIN7072221)

Target

Alle Tyrosinase-Related Protein 1 (TYRP1) Antikörper anzeigen
Tyrosinase-Related Protein 1 (TYRP1)

Antikörpertyp

Recombinant Antibody

Reaktivität

  • 195
  • 75
  • 9
  • 8
  • 6
  • 6
  • 6
  • 6
  • 5
  • 5
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
Human

Wirt

  • 106
  • 94
  • 1
Kaninchen

Klonalität

  • 131
  • 69
  • 1
Chimeric

Konjugat

  • 74
  • 16
  • 12
  • 11
  • 11
  • 11
  • 11
  • 11
  • 11
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Tyrosinase-Related Protein 1 Antikörper ist unkonjugiert

Applikation

  • 108
  • 83
  • 66
  • 39
  • 39
  • 27
  • 25
  • 14
  • 14
  • 12
  • 7
  • 5
  • 4
  • 3
  • 1
Immunofluorescence (IF), Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP)

Klon

TA99
  • Verwendungszweck

    Anti-TRP-1, gp75 [TA99], Rabbit IgG, kappa

    Spezifität

    Binds Tyrosinase-related protein-1 (TRP-1), a 70-75k enzyme located in melanocytes, which are specialized cells that produce a pigment called melanin, helping to stabilize tyrosinase, which is the enzyme responsible for the first step in melanin production and determine the shape of melanosomes, which are the structures in melanocytes where melanin is produced.

    Produktmerkmale

    Original Species of Ab: Mouse

    Original Format of Ab: IgG2a

    Aufreinigung

    Protein A affinity purified

    Immunogen

    70-75 kDa pigmentation-associated glycoprotein in human melanoma cell lines.

    Isotyp

    IgG kappa
  • Applikationshinweise

    This antibody binds to human and murine TRP-1 and had been under evaluation for the treatment of tumours.

    Kommentare

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1 mg/mL

    Buffer

    PBS with 0.02 % Proclin 300.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Target

    Tyrosinase-Related Protein 1 (TYRP1)

    Andere Bezeichnung

    TRP-1, gp75

    Hintergrund

    Melanoma antigen gp75, 5,6-dihydroxyindole-2-carboxylic acid oxidase, DHICA oxidase, Catalase B, Glycoprotein 75, Tyrosinase-related protein 1, TRP, TRP-1, TRP1

    UniProt

    P17643
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