GZMB Antikörper (FITC)
-
- Target Alle GZMB Antikörper anzeigen
- GZMB (Granzyme B (GZMB))
-
Reaktivität
- Human, Non-Human Primate
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser GZMB Antikörper ist konjugiert mit FITC
-
Applikation
- Flow Cytometry (FACS)
- Spezifität
- The mouse monoclonal antibody CLB-GB11 recognizes granzyme B, a 31 kDa serine protease expressed intracellularly in activated Tc cells and NK cells.
- Aufreinigung
- Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Immunogen
- Human NK cell line YT-INDY-derived granzyme B
- Klon
- CLB-GB11
- Isotyp
- IgG1
- Top Product
- Discover our top product GZMB Primärantikörper
-
anti-Granzyme B (GZMB) (AA 21-247) antibody
GZMB Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 73-187) antibodyGZMB Reaktivität: Human WB, IHC, StM Wirt: Maus Monoclonal GZMB-3014 unconjugated
anti-Granzyme B (GZMB) antibodyGZMB Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CLB-GB11 unconjugated
anti-Granzyme B (GZMB) (AA 21-130) antibodyGZMB Reaktivität: Human, Maus WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 175-203), (C-Term) antibodyGZMB Reaktivität: Human WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB19353 unconjugated
anti-Granzyme B (GZMB) (AA 21-247) antibodyGZMB Reaktivität: Human WB, IHC, ELISA Wirt: Maus Monoclonal 2G12G7 unconjugated
anti-Granzyme B (GZMB) (AA 1-247) antibodyGZMB Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 73-187) antibodyGZMB Reaktivität: Human IHC, StM Wirt: Maus Monoclonal GZMB-3056 unconjugated
anti-Granzyme B (GZMB) antibodyGZMB Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 21-247) antibodyGZMB Reaktivität: Human WB, IHC, IF, IHC (p) Wirt: Maus Monoclonal 4E4 unconjugated
-
- Applikationshinweise
- Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests. Intracellular staining.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
-
- Target
- GZMB (Granzyme B (GZMB))
- Andere Bezeichnung
- Granzyme B (GZMB Produkte)
- Synonyme
- CCPI antikoerper, CGL-1 antikoerper, CGL1 antikoerper, CSP-B antikoerper, CSPB antikoerper, CTLA1 antikoerper, CTSGL1 antikoerper, HLP antikoerper, SECT antikoerper, granzyme B antikoerper, GZMB antikoerper
- Hintergrund
- Granzyme B,Granzyme B is a serine protease that is expressed in cytoplasmic granules of cytotoxic T lymphocytes and NK cells. Vectorial secretion of perforin and granzymes is responsible for their granule-mediated cytotoxicity. Granzyme B plays a pivotal role in the induction of apoptosis in the target cells by activation of caspases. Moreover, granzyme B was reported to cleave directly alpha-tubulin, leading to perturbation of microtubule networks during the induced cell death.,GZMB, HLP, CTLA1, SECT
- Gen-ID
- 3002
- UniProt
- P10144
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose
-
