ATF2 Antikörper (pThr71)
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- Target Alle ATF2 Antikörper anzeigen
- ATF2 (Activating Transcription Factor 2 (ATF2))
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Bindungsspezifität
- pThr71
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ATF2 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Produktmerkmale
- Phosphorylated antibody
- Aufreinigung
- Affinity purification
- Immunogen
- A synthetic phosphorylated peptide around T71 of human ATF2 (NP_001871.2).
- Isotyp
- IgG
- Top Product
- Discover our top product ATF2 Primärantikörper
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- Applikationshinweise
- IHC 1:50-1:100 IF 1:50-1:100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- ATF2 (Activating Transcription Factor 2 (ATF2))
- Andere Bezeichnung
- ATF2 (ATF2 Produkte)
- Hintergrund
- This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene
- Gen-ID
- 1386
- UniProt
- P15336
- Pathways
- MAPK Signalweg, RTK Signalweg, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
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