CHEK1 Antikörper
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- Target Alle CHEK1 Antikörper anzeigen
- CHEK1 (Checkpoint Kinase 1 (CHEK1))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CHEK1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Produktmerkmale
- Polyclonal Antibody
- Aufreinigung
- Affinity purification
- Immunogen
- A synthetic peptide of human CHEK1
- Isotyp
- IgG
- Top Product
- Discover our top product CHEK1 Primärantikörper
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- Applikationshinweise
- WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CHEK1 (Checkpoint Kinase 1 (CHEK1))
- Andere Bezeichnung
- CHEK1 (CHEK1 Produkte)
- Hintergrund
- The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.
- Molekulargewicht
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Observed_MW: 54 kDa
Calculated_MW: 43 kDa/50 kDa/54 kDa
- Gen-ID
- 1111
- UniProt
- O14757
- Pathways
- p53 Signalweg, Apoptose, Zellzyklus, DNA Reparatur
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