ERCC2 Antikörper
Kurzübersicht für ERCC2 Antikörper (ABIN7257960)
Target
Alle ERCC2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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    - 
                                            Produktmerkmale
- Polyclonal Antibody
- 
                                            Aufreinigung
- Affinity purification
- 
                                            Immunogen
- Recombinant fusion protein of human ERCC2 (NP_001124339.1).
- 
                                            Isotyp
- IgG
 
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- 
    - 
                                            Applikationshinweise
- WB 1:500-1:2000
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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- 
    - 
                                            Format
- Liquid
- 
                                            Konzentration
- 1 mg/mL
- 
                                            Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 
                                            Konservierungsmittel
- Sodium azide
- 
                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            Lagerung
- -20 °C
- 
                                            Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
 
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    - ERCC2 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2))
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                                            Andere Bezeichnung
- ERCC2
- 
                                            Hintergrund
- The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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                                            Molekulargewicht
- 
                        Observed_MW: 80 kDa Calculated_MW: 46 kDa/86 kDa 
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                                            Gen-ID
- 2068
- 
                                            UniProt
- P18074
- 
                                            Pathways
- DNA Reparatur
 Target
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