ERCC2 Antikörper

Produktnummer ABIN7267057

Produktdetails anti-ERCC2 Antikörper

Target: ERCC2 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ERCC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Verwendungszweck: XPD/ERCC2 Rabbit mAb

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human XPD/ERCC2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ERCC2

Target: ERCC2 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2))

Andere Bezeichnung: XPD (ERCC2 Produkte)

Synonyme: COFS2 antikoerper, EM9 antikoerper, TTD antikoerper, XPD antikoerper, AA407812 antikoerper, AU020867 antikoerper, AW240756 antikoerper, CXPD antikoerper, Ercc-2 antikoerper, MGC89573 antikoerper, CG9433 antikoerper, DhR3 antikoerper, DhXPD antikoerper, DmXPD antikoerper, Dmel\\CG9433 antikoerper, ERCC2 antikoerper, XPD/ERCC2 antikoerper, l(2)SH2 2137 antikoerper, l(2)SH2137 antikoerper, xpd antikoerper, zgc:56365 antikoerper, ERCC excision repair 2, TFIIH core complex helicase subunit antikoerper, excision repair cross-complementing rodent repair deficiency, complementation group 2 antikoerper, excision repair cross-complementation group 2 antikoerper, Xeroderma pigmentosum D antikoerper, ERCC2 antikoerper, Ercc2 antikoerper, ercc2 antikoerper, Xpd antikoerper

Hintergrund: The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,ERCC2, COFS2, EM9, TFIIH, TTD, TTD1, XPD, ERCC excision repair 2, TFIIH core complex helicase subunit,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cell Biology & Developmental Biology,Apoptosis,XPD

Molekulargewicht: 75kDa

Gen-ID: 2068

UniProt: P18074

Pathways: DNA Reparatur