ERCC2 Antikörper (Internal Region)
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- Target Alle ERCC2 Antikörper anzeigen
- ERCC2 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ERCC2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Schimpanse
- Kreuzreaktivität (Details)
- Chimpanzee (100 %)
- Produktmerkmale
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Rabbit Polyclonal antibody to ERCC2 (excision repair cross-complementing rodent repair deficiency, complementation group 2)
ERCC2 antibody [N2C2], Internal - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human ERCC2. The exact sequence is proprietary.
- Isotyp
- IgG
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- Applikationshinweise
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
- Kommentare
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Positive Control: IMR32 , U87-MG
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- ERCC2 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2))
- Andere Bezeichnung
- ERCC2 (ERCC2 Produkte)
- Synonyme
- COFS2 antikoerper, EM9 antikoerper, TTD antikoerper, XPD antikoerper, AA407812 antikoerper, AU020867 antikoerper, AW240756 antikoerper, CXPD antikoerper, Ercc-2 antikoerper, MGC89573 antikoerper, CG9433 antikoerper, DhR3 antikoerper, DhXPD antikoerper, DmXPD antikoerper, Dmel\\CG9433 antikoerper, ERCC2 antikoerper, XPD/ERCC2 antikoerper, l(2)SH2 2137 antikoerper, l(2)SH2137 antikoerper, xpd antikoerper, zgc:56365 antikoerper, ERCC excision repair 2, TFIIH core complex helicase subunit antikoerper, excision repair cross-complementing rodent repair deficiency, complementation group 2 antikoerper, excision repair cross-complementation group 2 antikoerper, Xeroderma pigmentosum D antikoerper, ERCC2 antikoerper, Ercc2 antikoerper, ercc2 antikoerper, Xpd antikoerper
- Hintergrund
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The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Nucleus - Molekulargewicht
- 87 kDa
- Gen-ID
- 2068
- Pathways
- DNA Reparatur
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